No. 1688, Gaoke East Road, Pudong new district, Shanghai, China.
No. 1688, Gaoke East Road, Pudong new district, Shanghai, China.
Gallium-67 has a physical half-life of 78.3 hours and decays by electron capture, emitting gamma radiation. What happens when Gallium 67 enters the body? Although large amounts of radiation can increase your risk of cancer, the exposure from a gallium scan is very small. It's less than what is used for many types of X-rays.
The clinical impact of gallium-67 scintigraphy before and after therapy for lymphoma remains controversial. The aims of this study were: (1) to compare the staging of lymphoma by 67 Ga scintigraphy only with staging by clinical examination and conventional imaging (CI), and (2) to analyse the clinical relevance of both 67 Ga imaging and CI after treatment.
Background. 2-[fluorine-18]fluoro-2-deoxy-D-glucose–positron emission tomography (PET) and gallium-67 citrate (gallium) response after chemotherapy are powerful prognostic factors in diffuse large B-cell lymphoma (DLBCL).However, clinical outcomes when consolidation radiation therapy (RT) is administered are less defined.
Twenty control patients without cardiac disease had negative gallium-67 scans. We conclude that gallium-67 myocardial scintigraphy may be a useful test for predicting the response to prednisone and azathioprine therapy.
Gallium-67 Single Photon Emmision Computerised Tomography (SPECT) is a sensitive and cost effective tool in monitoring the disease activity of MOE, and should be used in the assessment of the response to antibiotic therapy.
Gallium Citrate Ga 67 Injection is supplied sterile and non-pyrogenic for intravenous use. Each mL contains 74 MBq (2 mCi) of Gallium Ga 67 on the calibration date, as a complex formed from 9 ng Gallium Chloride Ga 67, 2 mg of sodium citrate, …
Gallium-67 Scintigraphy is used for two broad purposes: The first is to detect infection. The scan is particularly useful in detecting infection or inflammation in the spine, chest region and is also useful to investigate suspected infection in bones and joints of other regions.
A gallium scan is a type of nuclear medicine test that uses either a gallium-67 (67 Ga) or gallium-68 (68 Ga) radiopharmaceutical to obtain images of a specific type of tissue, or disease state of tissue. Gallium salts like gallium citrate and gallium nitrate may be used. The form of salt is not important, since it is the freely dissolved gallium ion Ga 3+ which is active.
Gallium-67 citrate is an isotope with a half-life of 78 h . Gallium-67 citrate was injected in patients on Day 1 with images taken by gamma camera at 48, 72 or 96 h after injection. The dose of gallium-67 citrate administered to each patient varied between 5 and 10 mCi (185–370 MBq).
Original article Clinical relevance of gallium-67 scintigraphy in lymphoma before and after therapy Corinne Delcambre1, Oumedaly Reman2, Michel Henry-Amar3, Anne-Marie Peny4, Margaret Macro2, Stéphane Cheze2, Jean-Yves Génot4, Alain Tanguy4, Odile Switsers1, Hoa Ly Van1, Jean-Etienne Couëtte1, Michel Leporrier2, Stéphane Bardet1 1 Service de Médecine Nucléaire, Centre François …
phy in assessing the response of lymphoma to therapy. Key Words: gallium-67; lymphoma; normal and abnormal uptake J Nucl Med Technol 2000; 28:221–232 Gallium is a Group IIIb transition metal. Gallium-67 is widely used in nuclear medicine as a tumor-imaging agent by gamma-emission scintigraphy. Nearly 30 y ago, Edwards and Hayes (1)
A gallium scan uses gallium citrate. It's a drug that has very small amounts of radioactive gallium. A day or two before your scan, your healthcare provider injects the gallium citrate into a vein in your arm. The gallium then travels all over your body. It builds up …
Therapy of disseminated B-cell lymphoma xenografts in severe combined immunodeficient mice with an anti-CD74 antibody conjugated with (111)indium, (67)gallium, or (90)yttrium Clin Cancer Res, 7 ( 2001 ), pp. 1505 - 1510
6. Gasparini M, Bombardieri E, Castellani M, et al: Gallium-67 scintigraphy evaluation of therapy in non-Hodgkin's lymphoma. J Nucl Med 39:1586-1590, 1998. 7. Front C, Bar-Shalom R, Mor M, et al; Hodgkin disease: Prediction of outcome with Ga-67 scintigraphy after one cycle of chemotherapy. Radiology 210:487-491, 1999. 8. Line BR, Fulmer JD ...
Gallium. Generic name: gallium (GAL-ee-uhm) Brand name: Ganite. Uses. Before taking. Directions. Warnings. Side effects. Using gallium with other medicines that may harm the kidneys (eg, aminoglycosides [eg, gentamicin], amphotericin B) may increase your risk of …
title = "Gallium-67 scintigraphy evaluation of therapy in non-Hodgkin's lymphoma", abstract = "Patients with diffuse large cell lymphoma may achieve complete remission (CR) after chemotherapy, and the time to reach CR may be predictive of treatment outcome.
Gallium Ga 67, with a half-life of 78.3 hours, is cyclotron produced by the proton irradiation of enriched zinc oxide, is essentially carrier-free and contains negligible concentrations of other radioactive isotopes. The radionuclidic composition at calibration time is ≥99.89% Gallium Ga 67, ≤0.01% Gallium
Gallium-67 scanning in the evaluation of therapy of malignant tumors of the head and neck. Higashi T, Kashima I, Shimura K, Nakamura K, Sakurai S. Gallium-67 scintigraphy was performed on 25 patients with a variety of malignant tumors of the head and neck in order to evaluate the susceptibility of the tumors to irradiation and chemotherapy ...
Sequential quantitative Gallium-67 Citrate (Ga-67) scanning was used to evaluate the resolution of inflammation in standardized bruises in rat thighs with and without Helium Neon (He-Ne) laser treatment. The severity of inflammation in the injured tissue was assessed as the ratio of Ga-67 localized in the bruise to the Ga-67
We ascertained the difference in the level of pulmonary hilar (PH) gallium-67 (Ga-67) uptake in autoimmune pancreatitis (AIP) patients between the active (before corticosteroid therapy) and remittent (after 4 weeks of corticosteroid therapy) phases using a semiquan
Gallium (Ga 67) Citrate Injection contains the active ingredient called Gallium Ga 67 and belongs to a group of medicines called radiopharmaceutical agents, which are all radioactive. Gallium (Ga 67) Citrate Injection comes in a 10 mL vial and is available in three different radioactivities. It is ready for intravenous injection as packaged.
67 Ga imaging was used in a group of 13 untreated patients with documented South American blastomycosis in an attempt to obtain additional information on the site and extent of the lesions. All diagnoses were confirmed by demonstration of the fungi in the lesions or body fluids. Serologic tests were performed on all patients. 67 Ga imaging was correlated with X-ray in all patients, and with ...
Gallium-67 (67Ga) accumulates in malignant tissues via the transferrin receptor without need for a monoclonal antibody and emits cytotoxic low-energy electrons.
Gallium Ga 68 dotatate is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs. This medicine is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.
This investigation compared a noninvasive procedure, gallium-67 imaging, with endomyocardial biopsy in the detection of acute rejection in heart transplantation. Seven male patients (aged 41 to 54 years) sequentially had 46 gallium-67 scintigrams and 46 endomyocardial biopsies between 1 week and 8 months after transplantation.
In the GALLIUM trial, we compared the efficacy and safety of induction with obinutuzumab, as compared with rituximab, each combined with chemotherapy, followed by maintenance therapy with the same ...
Gallium-67 scintigraphy to predict response to therapy in active lupus nephritis. Lin WY(1), Lan JL, Wang SJ. Author information: (1)Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan. Gallium-67-citrate has been used to detect inflammation for decades, and 67Ga uptake usually indicates an active, potentially curable lesion.
Find patient medical information for gallium-67 citrate intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Clinical value of gallium-67 SPECT scintigraphy in the diagnostic and therapeutic evaluation of retroperi-toneal fibrosis: a prospective study. J Intern Med 2007; 262: 224–234. Background. Gallium-67 (67Ga) scintigraphy may be useful in evaluating patients with retroperitoneal fibro-sis (RPF), but a systematic assessment of its value is ...
Gallium-67 (67Ga) accumulates in malignant tissues via the transferrin receptor without need for a monoclonal antibody and emits cytotoxic low-energy electrons. In this study we investigated the feasibility, pharmacokinetics, toxicity and preliminary efficiency of high-dose 67Ga injected intravenously (i.v.) in patients with acute leukaemia not ...
We have prospectively evaluated the ability of gallium-67 citrate (Ga-67) imaging to define residual disease and predict outcome in 37 consecutive patients with DLCL. Patients received 296 to 370 megabecquerels (MBq) Ga-67 and were imaged prior to, following cycles 4 to 6, and at completion of intensive chemotherapy.
Myocardial gallium-67 scintigraphy may therefore be useful to predict the effect of corticosteroid therapy. In conclusion, the diagnosis of cardiac sarcoidosis with enlarged CTR, ventricular arrhythmias, or heart block may be too late to prevent cardiac accidents, because these cardiac signs are based on the permanent myocardial derangements ...
Early studies of 67 gallium (67 Ga) scanning in sarcoidosis focused on the lungs as a measure of disease activity, likelihood of progression, and the advisability of corticosteroid therapy. The predictive value of pulmonary uptake proved to be limited, but there has been renewed interest in 67 Ga scanning as a diagnostic aid with special attention to characteristic extrapulmonary uptake patterns.
A repeat gallium-67 scintigraphy after 2 weeks of intravenous antibiotic therapy showed a significant response with resolution of almost all the focal areas of increased uptake in pretherapy scan (arrows) indication of good response. The patient was shifted to oral antibiotics and to be seen in …
Pulmonary function was tested before and after therapy. Increase in vital capacity after treatment ranged from 40 to 1,030 ml; 12 of the 16 patients studied had an increase of more than 200 ml. There was a close correlation between the percentage uptake of gallium scan and the increase of the vital capacity after therapy (r = 0.95, p less than ...
